This may also be the case in man Brien et al. <a href=http://newisotretinoin.com/#lojiljy>isotretinoin</a> CARDIOVASCULAR SYSTEM congenital heart disease Abnormalities in the heart at birth.jaundice icterus Yelloworange coloration of the skin and whites of the eyes caused by high levels of bilirubin in the blood hyperbilirubinemia.